Commelina benghalensis is a perennial herb, used in the traditional medicine System for the treatment of various ailments like leprosy, sore throat, opthalmia, bums, pain and inflaimnation and also used as de-pressant, demulcent, emollient and laxative. In the present study, etlianol extract of C. benghalensis roots was phannacologically investigated to evaluate peripherally acting analgesic activity by acetic acid-in-duced writhing in Swiss Albino mice and centrally acting analgesic activity by hot-plate and tail-flick tests in mice. Anti-inflammatory activity was also evaluated using the carrageenan-induced mice paw edema model. In ali the experiments, the extract was administered orally at the doses of 250 and 500 mg/kg body-weight. The etlianol roots extract demonstrated a significant (P)
Keywords: Commelina benghalensis, Coimnelinaceae, analgesic, Writliing, Hot-plate, Tail-flick, Anti-inflammatory