Original Article

CHEMICAL CHARACTERIZATION AND ANTIMICROBIAL EVALUATION OF STACHYS CITRINA SUBSP. CITRINA ESSENTIAL OIL

  • Gökalp İŞCAN
  • Betül DEMİRCİ
  • Fatih DEMİRCİ
  • Y. Bülent KÖSE
  • K. Hüsnü Can BAŞER

Received Date: 06.10.2011 Accepted Date: 12.01.2012 Turk J Pharm Sci 2012;9(2):219-224

Flowering aerial parts of Stachvs citrina Boiss. et Heldr. sıtbsp. citrina (Lamiaceae) being endemic for Tıırkev were subjected to hvdrodistili ati on to obtain the essential oil which was further analysed by GC-FID and GC-MS, simultaneously. 36 constituents were determined in the oil, where a-pinene (29.8%) and f-phellandrene (13.6%) w ere identifıed as the maiti components. The anticandidal and antibaeterial effects of the oil were evaluated by ıısing mierodilution method. The oil showed weak inhibitorv effects against the tested bacteria panel (1.25 to 5.0 mg/mL, MIC) whereas the Candida strains were inhibited at lower concentrations of the oil. Especiallv C. glabrata was inhibited at a concentration of0.078 mg/mL of the oil.

Keywords: Stachvs citrina sitbsp. citrina, Lamiaceae, Essential oil, Antibaeterial, Anticandidal