Original Article

Composition of Volatile Oil of the Aerial Parts, Flowers and Roots of Ferulago blancheana Post. (Apiaceae) Growing in Turkey and Determination of Their Antimicrobial Activities by Bioautography Method

  • Songül KARAKAYA
  • Gamze GÖĞER
  • C. Sibel KILIÇ
  • Betül DEMİRCİ

Received Date: 03.12.2015 Accepted Date: 04.02.2016 Turk J Pharm Sci 2016;13(2):173-180

Volatile oils from the aerial parts, flowers and roots of an endemic species Ferulago blancheana Post, were obtai-ned by hydrodistillation and analyzed by GC and GC/MS. Main components were found to be bornyl acetate (11.7%) and β-caryopyllene (10.2%); sabinene (23.2%), myrcene (17.5%); (E)-2-decenal (20.3%), caryopyllene oxide (17.8%) for the aerial parts, flowers and roots, respectively. Antimicrobial activity study with bioautography met-hod was performed against three different microorganisms; Pseudomonas aeruginosa ATCC 13388, Escherichia coli NRRL, Staphylococcus aureus ATCC BAA 1026, and Candida albicans ATCC 24433. The results showed that essential oils obtained from the aerial parts, flowers and roots were active against S. aureus and C. albicans, however essen-tial oils obtained from the aerial parts and roots were found to be less effective against S.aureus. In addition, no antibacterial effects were observed against P. aeruginosa.

Keywords: Ferulago blancheana, Apiaceae, Volatile oil, Bioautography method, GC/MS