Methanolic extracts of Artemisia L. taxons (Artemisia absinthium L., Artemisia arborescens L., Artemisia campestris L., Artemisia scoparia Waldst&Kit., Artemisia santonicum L., Artemisia vulgaris L. and Artemisia arborescens L.) were investigated for their cytotoxic activities against three human cancer cell lines, MCF7, A549, HeLa, and two human normal cell lines, A7R5 and 293T. The cytotoxic activities were analyzed by real-time cell analysis system measuring electrical impedance. Artemisia scoparia Waldst&Kit. showed significant effect on MCF7 (IC50: 34 ug/mL) and HeLa (IC50: 90 ug/mL). A. absinthium exhibited selective cytotoxic activity on MCF7 (IC50: 270 ug/mL).
Keywords: Artemisia, Cytotoxic, MCF7, A549, HeLa, A7R5, 293T.