Original Article

OMPARATIVE HPLC DETERMINATION OF IRIDOID CONTENTS IN VERONICA CUNEIFOLIA SUBSP. CUNEIFOLIA AND V. CYMBALARIA

  • F. Handan ÖZTUNCA
  • İclal SARAÇOĞLU
  • Ü. Şebnem HARPUT

Received Date: 23.12.2010 Accepted Date: 27.01.2011 Turk J Pharm Sci 2011;8(1):63-70

In our continued chemotaxonomic investigations on water soluble compounds of Veronica species, two additional species, Veronica cuneifolia subsp. cuneifolia and V cymbalaria were compared on the basis of their major components in iridoid fractions. Iridoid glucosides which are known as chemotaxonomical marker for this genus are investigated by HPLC-DAD system using different solvent systems. Seven iridoid glucosides; aucubin, catalpol, veronicoside, verproside, amphvcoside, verminoside and catalposide were identified for both species. In addition, J more iridoid glucosides, 6-0-veratrovlcatalposide and 6-O-isovanilloylcatalpol were determined from V. cymbalaria and isolated from its iridoid fractions. The presence of two rare iridoid glucosides in V. cymbalaria makes the plant interesting for the reclassification of Veronica species.

Keywords: Veronica species, iridoid glucosides, catalpol derivatives, HPLC