Original Article

SYNTHESIS OF SOME (5-CHLORO-2(3H)-BENZOTHIAZOLINONE-3-YL) ACETO/PROPANOHYDRAZIDES TOWARDS ANTIMICROBIAL AND ANTIVIRAL ACTIVITY

  • Tijen ÖNKOL
  • Bilge ÇAKIR
  • Shigeru ITO
  • Berrin ÖZÇELİK
  • M. Fethi ŞAHİN

Received Date: 12.02.2009 Accepted Date: 13.05.2009 Turk J Pharm Sci 2009;6(3):195-206

In this study, new eleven hydrazone derivatives of (5-chloro-2(3H)-benzothiazolinone-3-yl) aceto/propanohydrazide have been synthesized. Structures of the synthesized compounds have been elucidated by IR and 1H-NMR spectral data and their elemental analyses. All compounds were screened for their antiviral and antimicrobial activities aganist various virus, bacteria and fungi strains.

Keywords: 5-Chloro-2(3H)-benzothiazolinone, Hydrazone, Synthesis, Antimicrobial activity, Antiviral activity