Original Article

FATTY ACID PROFILE AND ANTIMICROBIAL EFFECT OF THE SEED OILS OF URTICA DIOICA AND V. PILULIFERA

  • Yüksel KAN
  • İlkay ORHAN
  • Ufuk KOCA
  • Berrin ÖZÇELİK
  • Sinem ASLAN
  • Murat KARTAL
  • Senay KÜSMENOĞLU

Received Date: 19.03.2008 Accepted Date: 10.09.2008 Turk J Pharm Sci 2009;6(1):21-30

In present study, our goal was to investigate the fatty acid composition of the seed oils obtained from Urtica dioica and U. pilulifera cultivated in Turkey by capillary gas chromatography-mass spectrometry (GC-MS). Linoleic acid was found to be the main fatty acid (44.29 % for U. dioica and 62.99 % for U. pilulifera), followed by oleic acid (34.93 % for U. dioica and 21.91 % for U. pilulifera). Trace amount of linolenic acid (0.55 %) was analyzed only in U. pilulifera. These two oils were also tested against Escherichia coli, Pseudomonas aeruginosa, Proteus mirabilis, Klebsiella pneumoniae, Acinetobacter baumannii, Staphylococcus aureus, Bacillus subtilis, and Enterococcus faecalis for their antibacterial activity along with Candida albicans and C. parapsilosis for their antifungal activity by microdilution method.

Keywords: Urtica dioica, Urtica pilulifera, Urticaceae, Fatty acid, GC-MS, Antimicrobial activity