E-ISSN: 2148-6247
Antioxidant Activities of Phenolic Compounds of Centaurea ensiformis P.H. Davis
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Original Article
VOLUME: 11 ISSUE: 1
P: 19-24
April 2014

Antioxidant Activities of Phenolic Compounds of Centaurea ensiformis P.H. Davis

Turk J Pharm Sci 2014;11(1):19-24
Süra BAYKAN EREL 1
Petek BALLAR 2
Canan KARAALP 1
1. Ege University, Faculty Of Pharmacy, Department Of Pharmaceutical Botany, 35100 Bornova, Izmir, Turkey
2. Ege University, Faculty Of Pharmacy, Department Of Biochemistry, 35100\R\Nbornova, Izmir, Turkey
No information available.
No information available
Received Date: 12.09.2012
Accepted Date: 20.02.2013
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ABSTRACT

The aim of the present study was to investigate the antioxidant activities of 11 phenolic compounds pre-viously isolated from an endemic Centaurea ensiformis P.H. Davis (Asteraceae) by 2,2-diphenyl-l-picryl-hydrazyl (DPPH) and ABTS decolorization assays. These compounds consisting of 2 phenolic glycosides (tacioside and protocatechuic acid), 2 acetophenon glycosides (picein and 4-hydroxyacetophenon 4-0-[6’-0-P-D-apiofuranosyl]-P-D-glucopyranoside). 1 coumarin glucoside (scopolin), 4 flavonoid glycosides (vicenin-2, schaftoside, neoschaftoside and clnysoeriol-7-O-mtinoside), 1 phenylpropanoid glycoside (sy-ringin) and 1 neolignan glucoside (dihydrodehydrodiconiferyl alcohol 4-O-P-D-glucopyranoside). Protocatechuic acid and tachioside had the highest activity (DPPH IC50: 6.47 and 22.87 inM; TEAC: 33.2+0.18 and 31.2±0.99, respectively) in both methods. Dihydrodehydrodiconiferyl alcohol 4-O-P-D-glucopyranoside also showed liigh activity compared to ascorbic acid in DPPH assay (IC50: 27.7 inM). Our results concluded that the C. ensiformis liave a potential source of antioxidants of natural origin.

Keywords:
Centaurea ensiformis, Antioxidant activity, DPPH, ABTS, Protocatechuic acid, Tachioside.