FATTY ACID PROFILE AND ANTIMICROBIAL EFFECT OF THE SEED OILS OF URTICA DIOICA AND V. PILULIFERA

Turk J Pharm Sci 2009;6(1):21-30

1. Selçuk University, Faculty Of Agriculture, Department Of Field Crops, 42070 Konya, Turkey

2. Gazi University, Faculty Of Pharmacy, Department Of Pharmacognosy, 06330 Ankara, Turkey

3. Gazi University, Faculty Of Pharmacy, Department Of Pharmaceutical Microbiology, 06330 Ankara, Turkey

4. Ankara University, Faculty Of Pharmacy, Department Of Pharmacognosy, 06100 Ankara, Turkey

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Received Date: 19.03.2008

Accepted Date: 10.09.2008

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ABSTRACT

In present study, our goal was to investigate the fatty acid composition of the seed oils obtained from Urtica dioica and U. pilulifera cultivated in Turkey by capillary gas chromatography-mass spectrometry (GC-MS). Linoleic acid was found to be the main fatty acid (44.29 % for U. dioica and 62.99 % for U. pilulifera), followed by oleic acid (34.93 % for U. dioica and 21.91 % for U. pilulifera). Trace amount of linolenic acid (0.55 %) was analyzed only in U. pilulifera. These two oils were also tested against Escherichia coli, Pseudomonas aeruginosa, Proteus mirabilis, Klebsiella pneumoniae, Acinetobacter baumannii, Staphylococcus aureus, Bacillus subtilis, and Enterococcus faecalis for their antibacterial activity along with Candida albicans and C. parapsilosis for their antifungal activity by microdilution method.

Keywords:

Urtica dioica, Urtica pilulifera, Urticaceae, Fatty acid, GC-MS, Antimicrobial activity