E-ISSN: 2148-6247
IN VITRO CYTOTOXIC PROPERTIES OF SIX ARTEMISIA L. SPECIES
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Original Article
VOLUME: 8 ISSUE: 3
P: 247-252
December 2011

IN VITRO CYTOTOXIC PROPERTIES OF SIX ARTEMISIA L. SPECIES

Turk J Pharm Sci 2011;8(3):247-252
Süra BAYKAN EREL 1
Serdar Gökhan ŞENOL 2
Fadime AYDIN KÖSE 3
Petek BALLAR 3
1. Ege University, Faculty Of Pharmacy, Department Of Biochemistry, 35100 Bornova, Izmir, Turkey
2. Ege University, Faculty Of Science, Department Of Botany, 35100 Bornova, Izmir, Turkey
3. Ege University, Faculty Of Pharmacy, Department Of Pharmaceutical Botany, 35100 Bornova, Izmir, Turkey
No information available.
No information available
Received Date: 03.11.2010
Accepted Date: 06.01.2011
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ABSTRACT

Methanolic extracts of Artemisia L. taxons (Artemisia absinthium L., Artemisia arborescens L., Artemisia campestris L., Artemisia scoparia Waldst&Kit., Artemisia santonicum L., Artemisia vulgaris L. and Artemisia arborescens L.) were investigated for their cytotoxic activities against three human cancer cell lines, MCF7, A549, HeLa, and two human normal cell lines, A7R5 and 293T. The cytotoxic activities were analyzed by real-time cell analysis system measuring electrical impedance. Artemisia scoparia Waldst&Kit. showed significant effect on MCF7 (IC50: 34 ug/mL) and HeLa (IC50: 90 ug/mL). A. absinthium exhibited selective cytotoxic activity on MCF7 (IC50: 270 ug/mL).

Keywords:
Artemisia, Cytotoxic, MCF7, A549, HeLa, A7R5, 293T.