ABSTRACT

In the present study seven 5-chloro-2(3H)-benzoxazolinone-3-acetyl-2-(p-substituted benzal-hydrazone derivatives and four 5-chloro-2(3H)-benzoxazolinone-3-acetyl-2-(p-substituted acetophe-none)hydrazone derivatives were synthesized. Among them, the analytical data of five original compounds were given. In this study, the microwave synthesis method and antimicrobial evaluation of all the compounds were also reported for the first time. The minimum inhibition concentration (MIC) values of the compounds were determined by the Microdilution method using two Gram positive bacteria (Staphylococcus aureus, Bacillus subtilis), two Gram negative bacteria (Pseudomonas aeruginosa, Escherichia coli) and two yeast like fungi (Candida albicans, Candida parapsilosis).