E-ISSN: 2148-6247
PHENOLIC COMPOUNDS FROM THE ROOTS OF Atichusa azurea var. azurea
PDF
Cite
Share
Request
Original Article
VOLUME: 10 ISSUE: 2
P: 177-184
August 2013

PHENOLIC COMPOUNDS FROM THE ROOTS OF Atichusa azurea var. azurea

Turk J Pharm Sci 2013;10(2):177-184
Ayşe KURUÜZÜM-UZ 1
Zühal GÜVENALP 2
Cavit KAZAZ 3
L. Ömür DEMİREZER 1
1. Hacettepe University, Faculty Of Pharmacy, Department Of Pharmacognosy, 06100 Ankara, Turkey
2. Atatürk University, Faculty Of Pharmacy, Department Of Pharmacognosy, 25240 Erzurum, Turkey
3. Atatürk University, Faculty Of Sciences, Department Of Chemistry, 25240 Erzurum, Turkey
No information available.
No information available
Received Date: 22.09.2011
Accepted Date: 05.07.2012
PDF
Cite
Share
Request

ABSTRACT

In Turkish folk medicine, Anchusa L. species have been used as wound healing and diuretic agents. This study was performed on methanolic extract of the roots of A. azurea Miller var. azurea was resulted in the isolation and structure elucidation of four flavonol glycosides, kaempferol 3-O-jiglucopyranoside (=Astragalin, 1), quercetin 3-O-ji-glucopyranoside (=Isoquercitrin, 2), quercetin 3-O-arhamnopyranosyl (l'"^-6")-fi-glucopyranoside (=Rutin, 3), kaempferol 3-O-a-rhamnopyranosyl (l'"^>6")-f3-glucopyranoside (4) and a phenolic acid, rosmarinic acid (5). The structures of the isolated compounds were determined by spectroscopic methods [ID and 2D NMR spectra and MS]. This is the first report on the isolation of phenolic compounds from the roots of A. azurea.

Keywords:
Anchusa azurea, Boraginaceae, Phenolic compoimds, Flavonol glycosides, Rosmarinic acid.