E-ISSN: 2148-6247
Quantification of Shikimic Acid in the Methanolic Extracts of Three Alnus Taxons Growing in Turkey
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Short Communication
VOLUME: 13 ISSUE: 1
P: 115-120
April 2016

Quantification of Shikimic Acid in the Methanolic Extracts of Three Alnus Taxons Growing in Turkey

Turk J Pharm Sci 2016;13(1):115-120
Çiğdem ALTINYAY 1
Burçin ERGENE ÖZ 2
Mehmet Levent ALTUN 2
1. The Ministry Of Health Of Turkey, Turkish Medicines And Medical Devices Agency, Ankara, Turkey
2. Ankara University, Faculty Of Pharmacy, Department Of Pharmacognosy, 06100\R\Ntandogan Ankara, Turkey
No information available.
No information available
Received Date: 02.04.2015
Accepted Date: 09.07.2015
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ABSTRACT

Shikimic acid is a phenolic acid which is known to possess several activities and it takes attention as a leading com-pound to some synthetic medicinal substances as well. In this study, high performance liquid chromatographic analyses were carried out in order to determine shikimic acid contents of Alnus glutinosa subsp. glutinosa, A. orien-talis var. orientalis and A. orientalis var. pubescens; acetonitrile and 0.2% o-phosphoric acid:water mixture with isocratic flow was used as mobile phase. The flow rate was 0.5 ml/min. The quantitative analysis of methanol extracts prepared from the leaves of A. glutinosa subsp. glutinosa, A. orientalis var. orientalis and A. orientalis var. pubescens revealed that shikimic acid amount was found to be 0.6491%, 0.4309% and 0.2452% respectively.

Keywords:
Alnus, Betulaceae, HPLC, Quantitative analysis, Shikimic acid